Wednesday’s MLB Computer Picks & Best Bets – June 26

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The Cleveland Guardians versus the Baltimore Orioles is one of 16 strong options on today’s MLB slate, and we have best bets for each game in this article.

MLB picks today

Seattle Mariners at Tampa Bay Rays Odds, Lines & Predictions

Game info

  • When: 12:10 PM ET
  • Where: Tropicana Field
  • TV Channel: ROOT Sports NW
  • Records: Rays (40-41), Mariners (46-37)
  • Best bets

  • Moneyline: Rays (-115) | Mariners (-105)
  • Computer Moneyline Pick: Rays over the Mariners
  • Total: 7
  • Computer Total Prediction: Over (7)
  • Watch MLB all season long on Fubo

    Pittsburgh Pirates at Cincinnati Reds Odds, Lines & Predictions

    Game info

  • When: 1:10 PM ET
  • Where: Great American Ball Park
  • TV Channel: BSOH
  • Records: Reds (37-43), Pirates (39-41)
  • Best bets

  • Moneyline: Reds (-125) | Pirates (+105)
  • Computer Moneyline Pick: Reds over the Pirates
  • Total: 10
  • Computer Total Prediction: Under (10)
  • Watch MLB all season long on Fubo

    Philadelphia Phillies at Detroit Tigers Odds, Lines & Predictions

    Game info

  • When: 1:10 PM ET
  • Where: Comerica Park
  • TV Channel: MLB Network
  • Records: Tigers (37-43), Phillies (53-27)
  • Best bets

  • Moneyline: Phillies (-165) | Tigers (+140)
  • Computer Moneyline Pick: Phillies over the Tigers
  • Total: 9
  • Computer Total Prediction: Over (9)
  • Watch MLB all season long on Fubo

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    Atlanta Braves at St. Louis Cardinals Odds, Lines & Predictions

    Game info

  • When: 1:45 PM ET
  • Where: Busch Stadium
  • TV Channel: BSMW
  • Records: Cardinals (40-38), Braves (44-33)
  • Best bets

  • Moneyline: Braves (-130) | Cardinals (+110)
  • Computer Moneyline Pick: Braves over the Cardinals
  • Total: 7.5
  • Computer Total Prediction: Over (7.5)
  • Watch MLB all season long on Fubo

    Texas Rangers at Milwaukee Brewers Odds, Lines & Predictions

    Game info

  • When: 2:10 PM ET
  • Where: American Family Field
  • TV Channel: BSWI
  • Records: Brewers (48-33), Rangers (37-43)
  • Best bets

  • Moneyline: Rangers (-125) | Brewers (+105)
  • Computer Moneyline Pick: Brewers over the Rangers
  • Total: 8.5
  • Computer Total Prediction: Over (8.5)
  • Watch MLB all season long on Fubo

    Miami Marlins at Kansas City Royals Odds, Lines & Predictions

    Game info

  • When: 2:10 PM ET
  • Where: Kauffman Stadium
  • TV Channel: BSKC
  • Records: Royals (44-38), Marlins (28-52)
  • Best bets

  • Moneyline: Royals (-227) | Marlins (+180)
  • Computer Moneyline Pick: Royals over the Marlins
  • Total: 9
  • Computer Total Prediction: Under (9)
  • Watch MLB all season long on Fubo

    Colorado Rockies at Houston Astros Odds, Lines & Predictions

    Game info

  • When: 2:10 PM ET
  • Where: Minute Maid Park
  • TV Channel: COLR
  • Records: Astros (40-40), Rockies (27-53)
  • Best bets

  • Moneyline: Astros (-175) | Rockies (+145)
  • Computer Moneyline Pick: Astros over the Rockies
  • Total: 8.5
  • Computer Total Prediction: Over (8.5)
  • Watch MLB all season long on Fubo

    Oakland Athletics at Los Angeles Angels Odds, Lines & Predictions

    Game info

  • When: 4:07 PM ET
  • Where: Angel Stadium of Anaheim
  • TV Channel: BSW
  • Records: Angels (33-46), Athletics (29-54)
  • Best bets

  • Moneyline: Angels (-125) | Athletics (+105)
  • Computer Moneyline Pick: Angels over the Athletics
  • Total: 9
  • Computer Total Prediction: Under (9)
  • Watch MLB all season long on Fubo

    Washington Nationals at San Diego Padres Odds, Lines & Predictions

    Game info

  • When: 4:10 PM ET
  • Where: PETCO Park
  • TV Channel: SDPA
  • Records: Padres (44-41), Nationals (38-42)
  • Best bets

  • Moneyline: Padres (-189) | Nationals (+155)
  • Computer Moneyline Pick: Padres over the Nationals
  • Total: 7.5
  • Computer Total Prediction: Over (7.5)
  • Watch MLB all season long on Fubo

    Cleveland Guardians at Baltimore Orioles Odds, Lines & Predictions

    Game info

  • When: 6:35 PM ET
  • Where: Oriole Park at Camden Yards
  • TV Channel: BSGL
  • Records: Orioles (49-30), Guardians (51-26)
  • Best bets

  • Moneyline: Orioles (-189) | Guardians (+155)
  • Computer Moneyline Pick: Orioles over the Guardians
  • Total: 9
  • Computer Total Prediction: Under (9)
  • Watch MLB all season long on Fubo

    Toronto Blue Jays at Boston Red Sox Odds, Lines & Predictions

    Game info

  • When: 7:10 PM ET
  • Where: Fenway Park
  • TV Channel: NESN
  • Records: Red Sox (43-37), Blue Jays (36-43)
  • Best bets

  • Moneyline: Red Sox (-155) | Blue Jays (+125)
  • Computer Moneyline Pick: Blue Jays over the Red Sox
  • Total: 9.5
  • Computer Total Prediction: Under (9.5)
  • Watch MLB all season long on Fubo

    New York Yankees at New York Mets Odds, Lines & Predictions

    Game info

  • When: 7:10 PM ET
  • Where: Citi Field
  • TV Channel: Amazon Prime Video
  • Records: Mets (38-39), Yankees (52-29)
  • Best bets

  • Moneyline: Yankees (-130) | Mets (+110)
  • Computer Moneyline Pick: Yankees over the Mets
  • Total: 8.5
  • Computer Total Prediction: Over (8.5)
  • Watch MLB all season long on Fubo

    Atlanta Braves at St. Louis Cardinals Odds, Lines & Predictions

    Game info

  • When: 7:15 PM ET
  • Where: Busch Stadium
  • TV Channel: MLB Network
  • Records: Cardinals (40-38), Braves (44-33)
  • Best bets

  • Moneyline: Braves (-115) | Cardinals (-105)
  • Computer Moneyline Pick: Braves over the Cardinals
  • Total: 8.5
  • Computer Total Prediction: Under (8.5)
  • Watch MLB all season long on Fubo

    Los Angeles Dodgers at Chicago White Sox Odds, Lines & Predictions

    Game info

  • When: 8:10 PM ET
  • Where: Guaranteed Rate Field
  • TV Channel: SportsNet LA
  • Records: White Sox (21-60), Dodgers (50-31)
  • Best bets

  • Moneyline: Dodgers (-189) | White Sox (+155)
  • Computer Moneyline Pick: Dodgers over the White Sox
  • Total: 8.5
  • Computer Total Prediction: Over (8.5)
  • Watch MLB all season long on Fubo

    Minnesota Twins at Arizona Diamondbacks Odds, Lines & Predictions

    Game info

  • When: 9:40 PM ET
  • Where: Chase Field
  • TV Channel: ARID
  • Records: Diamondbacks (39-40), Twins (43-36)
  • Best bets

  • Moneyline: Twins (-120) | Diamondbacks (+100)
  • Computer Moneyline Pick: Diamondbacks over the Twins
  • Total: 9
  • Computer Total Prediction: Over (9)
  • Watch MLB all season long on Fubo

    Chicago Cubs at San Francisco Giants Odds, Lines & Predictions

    Game info

  • When: 9:45 PM ET
  • Where: Oracle Park
  • TV Channel: MARQ
  • Records: Giants (38-42), Cubs (37-43)
  • Best bets

  • Moneyline: Giants (-115) | Cubs (-105)
  • Computer Moneyline Pick: Giants over the Cubs
  • Total: 7.5
  • Computer Total Prediction: Over (7.5)
  • Watch MLB all season long on Fubo

    How to Bet on Baseball

    Get more MLB picks.
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    Cardinals vs. Reds Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

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    White Sox vs. Rockies Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    The Colorado Rockies (27-54) serve as underdogs on the moneyline (-105) in Saturday's contest versus the Chicago White Sox (23-61). Game time is set for 2:10 PM ET on NBCS-CHI. The Rockies are favored against the spread in this one...

    Mets vs. Astros Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    The New York Mets (40-39) and Houston Astros (40-41) meet Saturday at Citi Field, starting at 4:10 PM ET on WPIX. The Mets are -112 moneyline favorites for the contest, however, the Astros are favored against the spread of 1.5...

    Twins vs. Mariners Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    Willi Castro (11 games) will look to add to his hitting streak when the Minnesota Twins (45-37) and Seattle Mariners (47-37) meet Saturday at 10:10 PM ET, live on ROOT Sports NW from T-Mobile Park. Castro and the Twins are...

    Red Sox vs. Padres Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    A pair of surging power hitters meet Saturday when Rafael Devers -- with his three-game homer streak in tow -- and the Boston Red Sox (43-38) take on Kyle Higashioka (home runs in two straight) and the San Diego Padres...

    Tigers vs. Angels Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    The Los Angeles Angels (35-46) will look to Luis Rengifo, with homers in two straight games, to pull off an upset win over the Detroit Tigers (37-45) Saturday at Angel Stadium of Anaheim. The Tigers are -120 moneyline favorites for...

    Brewers vs. Cubs Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    The Milwaukee Brewers (49-33) roll into Saturday's matchup with the Chicago Cubs (38-45) looking to extend a five-game winning streak. The contest starts at 4:10 PM ET on MARQ with the Brewers listed as -133 favorites on the moneyline.Tobias Myers...

    Rays vs. Nationals Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    Following a two-homer game last time out, Jose Siri leads the Tampa Bay Rays (41-41) into action as -136 favorites against the Washington Nationals (38-43). First pitch from Tropicana Field at 4:10 PM ET on Saturday, live on MASN2.Aaron Civale...

    Royals vs. Guardians Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    The Kansas City Royals (46-38) and Cleveland Guardians (51-29) meet Saturday at Kauffman Stadium, starting at 4:10 PM ET on BSGL. The Royals are -110 moneyline favorites for the contest, however, the Guardians are favored against the spread of 1.5...

    Yankees vs. Blue Jays Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, June 29, 2024

    The Toronto Blue Jays (37-44), led by Isiah Kiner-Falefa on a 12-game hitting streak, will meet the New York Yankees (53-31) Saturday at Rogers Centre. The Yankees are -139 favorites for the matchup, which starts at 3:07 PM ET on...

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    Willi Castro (11 games) will look to add to his hitting streak when the Minnesota Twins (45-37) and Seattle Mariners (47-37) meet Saturday at 10:10 PM ET, live on ROOT Sports NW from T-Mobile Park. Castro and the Twins are...

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